Enyo.js is basically used for designed responsive web application and it enables the developers to create webpage that is fluid in nature, fast and perform perfectly on all types of resolutions.
Sencha is excited to announce the release of Ext JS 5, the newest version of our flagship application development framework.
This framework varies dramatically from the others in that a developers doesn’t need to understand or work with any of the front end trifecta — HTML, CSS or the DOM. All you need to master is the framework!
CorMVC is a jQuery-powered Model-View-Controller (MVC) framework that can aide in the development of single-page, web-based applications.
The beautiful, open source front-end SDK for developing hybrid mobile apps with HTML5.
Sproutcore powers a lot of high profile apps including MobileMe amongst others. Sproutcore has a steeper learning curve compared to the other options but makes up for it with developer productivity once he/she has learned the ropes.